The Dangers of Holiday Festivites…A PWS (USA) Alert

November 18, 2010

Risk of Stomach Necrosis and Rupture
Possibly Related to Chronic Gastroparesis
A Cause of Death from Sepsis, Gastric Necrosis or Blood Loss

Signs and symptoms of stomach necrosis and rupture:

  • Vomiting -Any vomiting is very unusual in Prader-Willi syndrome  
  • Loss of appetite- (ominous sign)
  • Lethargy
  • Complaints of pain, usually non-specific
  • Pain sensation is abnormal in Prader-Willi syndrome due to high pain threshold; rarely complain of pain
  • Pain is often poorly localized
  • Peritoneal signs may be absent
  • Abdominal/ stomach bloating and dilatation
  • Fever may or may not be present
  • Temperature regulation is altered in Prader-Willi syndrome
  • Guaiac positive stools (chronic gastritis)

THESE SIGNS SHOULD RAISE SUSPICION OF STOMACH NECROSIS/RUPTURE AS A POSSIBLE DIAGNOSIS WHICH CAN BE LIFE THREATENING!

History may include:

  • History of binge eating within the week
  • Hyperphagia and binge eating are characteristic of Prader-Willi syndrome, regardless of whether obese or slim
  • Frequently occurs after holiday, or social occasion with less supervision of intake
  • History of gastroparesis
  • Common in Prader-Willi syndrome, though often undiagnosed
  • Often slim or history of significant obesity followed by weight loss
  • May leave the stomach wall thinned

For more information go to www.pwsausa.org or call 800-926-4797.

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